The emergency department (ED) of Holby City Hospital is an accident and emergency ward encompassing several resuscitationsections, triage, cubicles, a walk-in centre, clinical decisions unit (CDU) and multiple executive conference rooms. The ED was built alongside the rest of the hospital in, or prior to, the early 1970s.[1] It has been remodelled since its initial construction several times.

The current Clinical Lead in the emergency department is Connie Beauchamp, who reports directly to the hospital's Medical Director. Responsible for the ED, walk-in centre and CDU, the Clinical Lead was a position established by the hospital's senior management team in 2002.